Wednesday, July 24, 2019

Dr. Steven Pandelidis: Endocrine Surgeon and Triathlete

Steven Pandelidis, M.D.
“I love it when I meet my dad’s former patients,” said surgeon Dr. Steven Pandelidis. “The other day I met a woman with her husband. She was in her 60s and she seemed to have it all put together. 

“She said,” he went on, “that my father saw her in his busy psychiatric practice thirty years ago, and that he took ‘great care’ of her. She said that she will ‘never forget’ what he told her:

“‘You are not crazy. You don’t need a psychiatrist. You just need to do three things: You need to get a new job, get a new car, and get a new husband.’”

The woman took this unconventional and surprisingly pragmatic advice, and, as things turned out, “He was absolutely right!” she said. 

“My dad should have been a surgeon,” said Steve, somewhat cryptically.

(Later on, trying to discern what he meant, my husband reminded me of Atul Gwande’s first book, “Complications.” Dr. Gwande expanded on what has been said, usually disapprovingly, about surgeons: that they are “sometimes wrong; never in doubt.”  Atul claimed that “this may (actually) be their strength.”  When faced with uncertainty and inexact science the physician wielding the knife must cut anyway; a decision needs to be made and action taken. Words may be thought of as scalpels too; cutting into, cutting away, and shaping the patient’s experience... But back to our story.)
Kirk Pandelidis, M.D.

Steve’s father (1927-2016) was an immigrant from Greece (after his own persecuted parents left Asia Minor, now Turkey). He settled in York to marry and practice psychiatry. Steve said that his father worked long hours, often seeing patients after dinner until ten at night, and that “he loved what he did.”  He “commanded respect” in the community and at the Greek Orthodox church, where he was affectionately referred to as “īātré.” 

(Another digression: I didn't understand the Greek word Steve used, and my mind drifted to our family trip to Greece 15 years ago.  On the worn Athens streets, I heard people softly calling out “Éla, Éla,” to one another. I wondered what it meant. Maybe it was just a strangely-popular name. On the last day of our stay I asked our taxi driver. He said, quietly, “It means to come closer.”)   

Anyway, despite his father’s hectic schedule, the family (he has an older brother and two sisters) always had supper together at six. His dad would sometimes talk about his patients (no names), and the “unbelievable chaos” in their lives.

While there was no push for Steve or his siblings to go into medicine, there was never talk of “doing anything different.” By the time he was in the “ninth or tenth grade” Steve “knew” he would go to medical school.

He graduated from high school in 1979 and during the following summer he served as a psychiatric aide (you read that right, he worked in psychiatry) at the York Hospital. He did this while majoring in French Literature (oui, Litterature franḉaise) at Haverford, and again after his first year of medical school at Penn State Hershey. (Steve dutifully followed his brother Nicholas to both schools, by the way.) 

While Steve found these summer interludes “interesting,” he was clearly not going to be a psychiatrist. He was not a fan of chaos. “How did you decide to go into general surgery?“ I asked.

During medical school, he did a fourth-year surgical rotation at York Hospital in plastic surgery. After that, he considered becoming an ENT (ear-nose-throat) specialist. Community practice had little appeal (ear tubes and tonsils and such) compared to a university setting where they did head and neck cancer surgery, but he did want not want to be an academic. At the last moment, he decided to do general surgery. But why? Because he “just liked it.” 

Where should he go next for training? 

“I thought I might come back to York (after medical school) because I am close with my family,” said Steve. So he applied to his hometown program.

Dr. Jonathan Rhoads, the director of the surgical program at the York Hospital, gladly accepted him for a residency. Steve “absolutely loved” the five years of intense work. He married his wife Julie during his third year of residency. He gradually absorbed the demanding craft of surgery and they kept things simple at home as they lived in an apartment over his father’s office just down the street from the hospital.  

(The psychiatric practice was named “Delphic” to honor his father’s Greek heritage. Delphic: pertaining to “ambiguous or enigmatic” advice or predictions.) 
Oracle at Delphi (from "The Greek Reporter")
“In two minutes I was at the hospital," said Steve. "No worries about where to park the car. No worries about traffic or safety.” Though he seeks challenges in his professional life and in athletics, he avoids unnecessary hurdles whenever possible.

And strenuous athletic activity is an important part of his routine. Dr. Pandelidis is a serious triathlete who swims, bikes, and runs on different days of the week according to his mood and the weather. He found “Bikram-style” Hot Yoga five years ago and is hooked. He wishes he had discovered it earlier.

The focus of the intense 90-minute classes in 104 studios is on three things: “flexibility, balance, and stamina.” They run through the same 26 gradually-more-difficult yoga poses plus two breathing exercises each session. The same sequence over and over. And wherever in the world these classes are given the routine is identical. “You can measure your own progress,” said Dr. Pandelidis. "You compete against yourself and try to improve. It’s pretty nifty.”  
"Everybody on your Toes!"
 (From a hot yoga session at Massachusetts General Hospital)
This predictable sameness, he noted, is part of the anciently ordered, comforting, ethereal, and meditative Orthodox Christian services he happily participates in nearly every Sunday morning with his wife (sometimes after a long mind-clearing run on the Rail-Trail). The Church liturgy has been essentially unchanged since the fifth century and brings people closer together as everyone chants it in unison.  

Anyway, we can leave the drippingly sweaty and scantily clad athletes in their yoga class and return to Steve's story. 

Yes, he liked general surgery well enough, but he also enjoyed the weekly “tumor board” conferences.  He listened as the “erudite” oncologists Dr. Miodrag Kukrika and Dr. Eamonn Boyle (each the subject of a previous story in this series) quoted studies about survival curves. He listened as the radiation-therapy specialist, Dr. Greg Fortier, did the same. He listened as one of the laconic cancer surgeons would grunt and confidently announce, “I can take it out!”

As he worked with Dr. Robert Davis (“an important mentor”) and with Dr. Tom Bauer, York’s first dedicated surgical oncologist, he saw an opportunity for his own career. He sought training in the new specialty and he took a two-year fellowship at the University of Illinois in Chicago. "They did a lot of melanomas, head and neck surgery, and a lot of breast cancer, but not many gastrointestinal malignancies,” he said. 

When he returned to York Steve joined six other surgeons in an independent group. As he focused on patients with specific cancers his practice evolved, and he views himself now as “an endocrine surgeon.”

I asked him what he enjoys, what he does best. His skill, he said, is doing thyroid and parathyroid surgery, and he does this more than 200 times a year. He told me that there is generally a predictable pattern to the procedures, and said that “if you do the same thing over and over you get better at it.”  (He confided later that he also relishes the test of an especially difficult surgical case every now and then.)   

When Steve started his career thyroid tumors were much less common than they are now. They were usually found during a physical exam; the gland was palpated, a nodule was felt, and an ultrasound was ordered. But most nodules he sees now happen to be discovered incidentally. They are found when looking for something else. Thyroid abnormalities may be seen, for example, on a CT scan of the chest done after a suspicious finding on a routine chest x-ray, or maybe after an ultrasound of the carotid when working up a stroke, or on an MRI of the cervical spine done for neck pain.
Thyroid nodule (arrow) found incidentally on a spine MRI
Such quiet growths, it turns out, are exceedingly common. As many as 30% of adult women have thyroid nodules, 90-95% of which are benign. To identify those that are cancerous is the issue. Small asymptomatic nodules can simply be followed by repeat imaging to see if they enlarge before a biopsy is needed. Larger nodules (more than 1 cm) and smaller, but symptomatic, nodules usually demand an ultrasound-guided fine needle biopsy for analysis. 

Dr. Pandelidis said that, as a result of the above, “there are too many ultrasounds, too many biopsies, too many surgeries, and too much (use of) radioactive iodine.”  The American College of Endocrinology and other similar bodies have developed guidelines to address this excess, but it will take time to change doctors' habits and patients' expectations.

I wondered if someone who’s been told now that they have a small thyroid nodule can cope with uncertainty so that they can leave it untouched while watching for the enlargement that suggests cancer.
The thyroid and the important surrounding structures
Steve responded, and said that there are very few women (nodules are three times as common in women as in men) who are willing to wait. Even when he explains to them that most thyroid cancers are very slow-growing and are almost always curable with surgery and radioactive iodine.
 
(Dr. Pandelidis reminded me that a similar dilemma is being seen as tiny breast cancers that might never cause harm are picked up on routine mammograms, sometimes leading to fear-driven mastectomy instead of the breast-conserving removal of just the tumor.) 


Through diligent practice, constant self-assessment, and immediate feedback, and by doing the same surgery again and again, Dr. Pandelidis has steadily refined his technique. He said that he can do a thyroidectomy as an outpatient in thirty minutes leaving only a nearly invisible scar. 

When the challenge is high and the skill level is matched, the surgeon, like the dedicated athlete or the performing musician, can be "in the flow." There is total immersion in the task that seems effortless, and there is a loss of sense of time and self. 
    Flow chart after Mihaly Csikszentmihalyi
     "Flow" is when the challenge and the skill level are matched
Reflecting on changes in the treatment of cancer since he first attended the stimulating weekly conferences decades ago, Steve said that “we are at a very interesting time.” 

Malignant melanoma is his other major surgical interest and there have been major advances recently in precision diagnosis and non-surgical treatment. This cancer has been increasing in frequency in the last 30 years and is now the fifth most common cancer. There were no new treatments for advanced or surgically inaccessible disease from 1995, when alpha-interferon 2-b was introduced, until a few years ago. 

The immune-based targeted therapies approved for melanoma like Opdivo (in 2017) and Keytruda (in 2019) “are amazing,” remarked Steve. These so-called PD-1 checkpoint inhibitors unblock the immune attack on run-away cancerous cells. They are being used to treat diseases that were “not getting a lot of attention” (compared to, for example, breast cancer). 

Patients that only a few years ago would have succumbed to their widespread cancer after a few months have now been “walking around for two or three years.”  Their “diffuse metastatic disease is all gone,” said Dr. Pandelidis with visible excitement.

His two main interests have something special in common. He said that he “chose (to treat) cancers where surgery makes all the difference in the world.” Where it was once thought that “it was the big surgery that cured breast cancer, now we know that it is the little surgery, along with the help of radiation, chemotherapy, and hormone treatment. But with melanoma, you remove the lesion and lymph nodes that it could have spread to, and most of the time you take care of it.”  Early diagnosis is still key. If in doubt about a spot on the skin that looks suspicious, "you should get that checked." 
ABCDE Mnemonic to help recognize a melanoma
Thyroid cancer treatment apart from the surgery is even simpler, and it is mostly just use of radioactive iodine (except for unusually aggressive and rare tumor types, where things get complicated and the medical oncologist steps in).

As we sat and talked together after his 40-mile morning bike ride with his wife, Dr. Pandelidis was surprisingly relaxed, and I was struck by the sense that he seemed to be an unusually happy doctor; I wanted to know more about that. 

I said that we are hearing that physicians have been stressed by changes in the way they are forced to practice in the era of cumbersome electronic health records and increasingly-intrusive insurance companies looking over their shoulders. What was his take?

He said that he “is generally a happy person” by nature (50-80% of general happiness may be genetic according to Haidt), but that he works at being happy too. For example, in his practice he delegates some of the tedious charting work. Simply ordering and arranging for a routine CT scan, a task that used to be straightforward now involves a long list of sequential steps, multiple mouse clicks, and data entry. He hands this off to his capable physician’s assistant. One more job for his support staff; one less headache for Steve. 
Documenting exercise, yes exercise, on Epic (from Kaiser Permanente)
Dr. Pandelidis told me that he serves on the WellSpan physician well-being council (yes, even doctors need doctoring in such things) where they address the increasingly-common problem of physician burnout. He listens to the stories and gladly shares his hard-won insights with his weary, less content, and struggling colleagues.

But making sure legal forms are signed, and carefully documenting procedures for the record are his responsibilities alone. This electronic “paperwork” eats into the precious time between surgical cases, the time he needs to ready himself properly for the next anxious patient.  He likes to talk to the patient’s family in the recovery room but, due to these constraints, he may (regrettably, he notes) resort to calling them on the phone instead.

But, even though his independent group decided to join the WellSpan system about four years ago and Dr. Pandelidis was reluctant to relinquish some of his highly valued autonomy. He has not let this alter his core values. 

He told me that after a surgical cure he still follows most of his patients yearly. They are comforted when he reassures them that their thyroid tumor or their melanoma has not returned. He makes sure that if they have not recently seen, or maybe don't even have a primary care physician they do not neglect other important health issues. He said that this follow-up has become a very rewarding and important part of his practice. 

And as he trains and guides surgical residents and students he transmits his way of the experienced physician-surgeon to the next generation. 

He teaches them to be flexible, to develop stamina, and to strive to be in balance (though they need not stand on their heads or their tippy-toes).


Suggested Readings:

1. Gawande, Atul. Complications: A Surgeon's Notes on an Imperfect Science. Picador. New York, 2002. 


2. Csikszentmihalyi, Mihaly. The Evolving Self: A Psychology for the Third Millennium. Harper Collins. New York, 1993.


3. Haidt, Jonathan. The Happiness Hypothesis: Finding Modern Truth in Ancient Wisdom. Basic Books. New York, 2006

Thursday, June 27, 2019

Dr. KimberLee Mudge: Surgeon With a Vision

KimberLee Mudge, M.D.
Looking out over her farm’s pasture after a long day of breast surgery is “just good for my soul,” said Dr. KimberLee Mudge.  And on weekends, “the labor of mucking stalls is cleansing and rewarding.” Sometimes her 15-year-old son Peter is with her, sharing the vision and the chores. She noted that “there is something to be said for doing what our ancestors did every day” and that “it feels good to be connected to the earth” and to “try to be sustainable.”

Thinking about my own Eastern European shtetl-living and likely mutant-tumor suppressor gene-carrying forebears I quickly respond: “I’m not exactly sure what my ancestors did, but I know they did not do that.”  We laughed together, and so began a relaxed and far-ranging interview.

“So, you have a farm?” I asked.

“When I finished my residency at York I bought this little 1881 house and worked to restore it. It was on three acres. I planted an orchard, and that evolved into a woodland hobby farm. I grow sour cherries, apples, rhubarb, potatoes, squash, and blueberries. Also, I have chickens, and a few beehives.”

“Are you getting ready for the apocalypse?”

“That is what my partners Tommy (Dr. Thomas Nicholson) and “Iggy” (Dr. Ignacio Prats) joke about. When something happens, they say, they are coming directly to the compound.”

Not one to sit still, Dr. Mudge has expanded her vision and is now working on an old log farmhouse on the part of her property where she has already set up a “fiber farm.”  She raises alpacas, llamas, and sheep (the males are rams and the females, ewes, I was kindly reminded later), and she has a few miniature donkeys (the male is a jack and the female is a jenny, for those interested in such things). She hopes to grow this into an educational tool, as “a way of giving back,” she told me.

Freshly-shorn llamas and alpacas in Dr. Mudge's pasture
“How in the world do you have the time to do all this and practice medicine too?”
“My days never stop. I have zero downtime. But I think it keeps me good,” she said. Her son (she is a single parent) does his chores on the farm before and after school. He was adopted from Siberia, she told me.

(Did she say Siberia?) “Did you have to go there to get him?” I asked.

“Yes, he was almost a year old and institutionalized.”  The abandoned children (most are not really orphans) have very limited physical contact and nurturing. “You read about this,” she said, “but until you see it, it is something else. For the first couple of years, Peter did not know how to look into people’s eyes. He smiled on his own terms, but not (in a) reactionary (way).”

“They didn’t hold him or comfort him enough?”

“Not really.”

“Did you know the situation of the orphanages in Russia before you went?”

“I used Bethany Christian (adoption services), out of Lancaster, and they had never gone to Siberia before." (She paused...reflecting...) "Usually, when I am given an opportunity, I think of it as a sign, and that I need to take it. So I did.”

“Go on.”

“It was a nightmare situation,” said Dr. Mudge. But “he was in relatively good health” compared to the other institutionalized kids she saw when she got to the embassy where they and Peter were eventually sworn in as U.S. citizens.

“Did you have times when you wanted to back out?” I wondered.

“No, but the Communist environment was straining,” she replied. “After the first trip, Peter did not come home with me. On the second, they needed a redo of the paperwork that they had already received. This was followed by an appeal, and (I had to) stand before the court, and the sit-in judge was not happy about my request.”  Though her attorney pleaded with the judge Dr. Mudge feared that they were going to decline the adoption; she sensed that the process was being “driven by (the quest for) the American dollar.” 


Russian Orphans (from Ekaterina Loushnokova)
But (and here is a crucial point) Dr. Mudge is not one to give up when the goal is vitally important to her; she admitted that she “is a bit of a fighter.” So she persisted, stood up against the formidable Russian bureaucracy, and was able to rescue her son from what would likely have been a sad life.  “It was horrible, but I have no regrets,” she said.

Two years after finding Peter she started the process of adopting a little girl from China. The Beijing Summer Olympics were approaching, and TV images of children leaving the country would not be good PR.  (Remember when we all watched the same three or four networks, remember when the news was a shared experience?) The Chinese government changed the rules again and again and Dr. Mudge was disheartened as her hard work failed, and she reluctantly withdrew her request.

Moving on: “How did you decide to become a doctor?” I asked.

“Everyone in my family (in north-central Pennsylvania) was a school teacher and education was important. It’s weird, as a youth I was terrified of death, but, somehow, I wanted to be a physician. My passion was for science. I wanted to be my own boss. I wanted to make a difference. I thought that in medicine I would have autonomy.”
Unspoiled farmland in north-central Pennsylvania
“Tell me more.”

“I have always tried to push the envelope as a woman,” said Dr. Mudge. “I went to college on a basketball scholarship from Marshall University in Huntington, West Virginia. They also had a young medical school there” (making it especially attractive to her). Before medical school, she got a master’s degree in biology. Altogether, she lived in Huntington for ten years. At that point, family, friends, and her “hometown folk” thought she should be a pediatrician or a family doctor.

But KimberLee the medical student needed “action” and, as a visual learner, surgery was the best fit; the days flew by during her surgical rotations and she was excited by what she saw and wanted to share that.

She graduated from medical school in 1991. When looking for a residency she longed to come back to her roots. She wanted to be close to family, but in a somewhat less rural setting than where she was raised. While a fourth-year medical student, she did a surgical rotation in York with Drs. Steve Pandelidis, Tom Scott, Samuel Laucks, Gil Rothrock, and Vasudevan Tiruchelvam.  As she reflected on that formative experience,  York seemed to be the ideal setting; she loved the “family feeling” of the York Hospital where everybody seemed to know each other, and where they worked together.
An old postcard of the stately-looking York Hospital
Surgery in the 1990s was shifting, and as a young surgeon, she went through her five-year residency she sensed the push towards subspecialization.  Dr. Mudge decided to focus on women’s health and she reached out to one of her valued medical school attendings. She asked if she knew of anyone specializing in breast surgery.  Her professor did, and KimberLee contacted Dr. Claire Carman in Norfolk, Virginia.

She spent six months (“with essentially no pay”) shadowing Dr. Carman and learning everything she could, came back to York,  and began her practice of breast surgery. “This has been a good fit,” she said. It filled a void, as there were no (local) women physicians dedicated solely to women’s health.  And, as an added bonus, “it just felt right” and it was who she was.
Claire Carman, M.D.
“What changes in surgery of the breast  have you seen over the past 21 years of practice?” I asked.

Dr. Mudge recalled that when she came to York in 1991 she would scrub in for cases where the woman was about to undergo general anesthesia for a breast biopsy. The consent form included the wording that she would agree to an immediate mastectomy if cancer was found during the procedure. Standing by the draped and prepped patient in the cold OR, and realizing that she was the only person in the room that the patient knew was humbling. Dr. Mudge felt that these women were the strongest people she had ever met, knowing, as they did, that they might wake up missing a breast. Thankfully, that doesn’t happen now, as women almost always know beforehand what to expect.

In fact, by the time she started practice, the simple removal of just the tumor itself, the so-called lumpectomy, was already becoming the standard of surgical care. Routine Identification of what is known as the sentinel lymph node in the axilla (the armpit) allowed for easier staging without the development of the feared permanently swollen arm of lymphedema. The disfiguring radical mastectomy was gone and even the less severe modified mastectomy was fading. Breast conservation was much preferred. But things don’t stay the same.
Modified radical mastectomy (from the National Cancer Institute)
Since the mid-1990s there have been remarkable advancements in genetic assessment of cancer risk and genomic evaluation of the tumor tissue. Since identifying a number of mutated genes that increase the risk of developing breast cancer, most notably some of the many variants (perhaps a thousand!) of mutated BRCA-1 and BRCA-2 (tumor suppressor) genes located on chromosomes 17 and 13, respectively (discovered by Mary-Claire King, Ph.D.), women are becoming more “empowered” according to Dr. Mudge.

For example, even knowing, as carriers of certain mutations, that their chance of having breast cancer by the age of 80 may be as high as 70%, many of these high-risk women are choosing to have close surveillance and breast-conserving procedures rather than a prophylactic mastectomy. The women will, however, often have their ovaries removed to eliminate the also-heightened risk of ovarian cancer, since monitoring for that isn’t very good, and while treatment options are improving, they are still poor.

(Note to the men who have gotten this far: Males of the species harboring the genetic BRCA2 mutations have about an 8% lifetime risk of breast cancer and a nearly 25% risk of prostate cancer. This genetic information, you see, is not just for women.)

While genetic testing can identify women with an increased risk for cancer, “genomic” testing of the tumor itself can help direct treatment.  For example, with a commercial 21-gene assay, a low “score” predicts a 2% rate of distant recurrence at 10 years that is unlikely to be improved by adjuvant chemotherapy (that can, therefore, be withheld). A high score, on the other hand, predicts benefit from chemotherapy. This “preventive” chemotherapy may reduce cancer deaths by up to 70%. Endocrine therapy is now often recommended first for women with hormone-sensitive (so-called estrogen- or progesterone-positive) tumors. Other markers such as HER2 must also be taken into consideration as various new treatments are developed.
Women's risk of breast cancer by age and BRCA status
Curiously, despite the many advances and options, young women with one-centimeter localized cancerous lesions that are not associated with known genetic mutations are often choosing to have a (simple) mastectomy and breast reconstruction. They don’t want to have the fear of another cancer hanging over their heads for decades. “They want to get on with their lives,” noted Dr. Mudge, as they consider “lifestyle” issues to be paramount.

Decisions, decisions. Education gives women the tremendous advantage of a fully-informed choice. So Dr. Mudge and members of her team spend a lot of time and effort to be sure that adequate information is provided to every woman, and that the women fully understand their options. The management of diseases of the breast is now exceedingly complex; there are benign but suspicious breast masses, clearly precancerous growths, sharply localized cancers, cancer that has spread to regional lymph nodes, and even cancer that has spread distally at the time of initial diagnosis. Patients need time and help to take it in.
One algorithm for breast cancer (from Onkopedia)
(BCS=Breast conservation surgery)
“Handling the intense emotions that accompany a breast cancer diagnosis must be difficult for you,” I say.

While there is a little bit of hand-holding, a softening, Dr. Mudge tries her best to be “a straight shooter” and she doesn’t “sugarcoat” things. After the anxiously awaited biopsy is completed the fear and anxiety continue. She knows this and makes sure to call with the pathology results as soon as they are available. Dr. Mudge notes that at the time of this phone conversation the women “are on their own territory” and they can react “on their own terms.” They may “cry or throw things,” but this happens in private. KimberLee then arranges for an office visit within 24-48 hours to work out a plan.

She writes everything down and gives them their reports. They need to be fully informed. And with that information, they are more empowered and, hopefully, less victimized. Dr. Mudge reviews everything, and the woman gets to know her surgeon and the support staff. They need to develop mutual trust and a true partnership.

Some patients have told Dr. Mudge that cancer is “the best thing that has ever happened” to them. She said that “many come out on the other side stronger and more confident.” They have “conquered the beast.” She said that “it is quite remarkable” as some move on, maybe from a spouse that was not right, or gone on to college and become nurses. It is courageous to work through suffering.

Not really knowing why, I ask if she is optimistic about the future of her still-independent practice.

When she came to the York Hospital she was pleased that there was a feeling of family throughout the community. But over the last 20 years, the health systems grew and spread. It seemed to her that “respect for the clinicians” was being slowly eroded, and that physicians were gradually becoming “expendable commodities.”

Countering this trend, Dr. Mudge said, is that her surgical practice has remained unique. She and her partners  “have all subspecialized” but collectively they “function as one general surgeon.” And it has been ingrained in them that they have a sacred responsibility to the patient, who always “comes first.”

As the continued autonomy of her practice, “Leader Surgical Services,”  is threatened by the large health conglomerates that control patient flow Dr. KimberLee Mudge has needed to expand her vision of the future.

What does she see?

Maybe a bright new facility dedicated to the comprehensive management of diseases of the breast.  A place where patients and staff work together seamlessly. Where there is a focus on early diagnosis when suspicious lesions are still small and easily removed. Where the surgical procedure is carefully fitted to the specific needs of the woman. Where postoperative and late follow-up care occur in a peaceful nourishing setting.

Where this setting is dotted by plantings of lavender and sunflowers. And vegetable patches.  And fruit trees. Where honeybees flit from blossom to blossom. Where patients and staff can walk on lovely winding paths together. Where there is mindfulness of the needs of future generations. Where sustainability is a guiding principle. Where everything is connected. Where there is family.

That would be a nice vision. Squinting, I can almost see it forming in the distance...


Dr. Mudge's animals are watching us...

Suggested additional readings (from my husband's bookshelf):

1.  Capra, Fritjof. The Web of Life. Anchor Books, New York, 1996.

2.  Mukherjee, Siddhartha. The Gene: An Intimate History. Scribner, New York, 2016.

3.  Wilson, Edward O. The Future of Life. Vintage Books, New York, 2002. 



By Anita Cherry 6/27/19

Monday, June 3, 2019

Dr. Ed Rogers: Holistic Medicine


Ed Rogers, M.D.
Find a comfortable position. Take a slow full breath through your nose. Hold this in-breath for five seconds. Then slowly exhale. Repeat. And again. Did you, perhaps, note an interaction between the mind and your body? Did you begin to feel a subtle change? I sat down with York internist Dr. Ed Rogers who focused much of his energy on bringing the mind and body together in his medical practice. How did he get there?

“I grew up Catholic and went to parochial school till the sixth grade,” he said. “What the nuns did really well, what I took away from them was this: the sense that everything about Life and God was a mystery with a capital M.  Even as a young boy he knew that there was something out there “greater than us.” And he wanted to mingle with that Mystery.

Born in Baltimore, Dr. Rogers grew up in Pasadena, between Baltimore and Annapolis.  He and his two brothers often played by the Chesapeake Bay. (Sadly, his younger brother has passed away.) They had fun in nature. When it was time, his father, an architect, told his son that he needed “a reason” for going to college.

Ed thought of following his father’s fine example, but being left-handed, his father warned him, would be a huge disadvantage (before computer-aided drafting made that irrelevant). He should probably look elsewhere. Ed listened. He wanted to find something that was valuable in itself and he was drawn to the idea of medicine.     

He majored in zoology (actually biology) at Duke, but was careful to take courses outside of the hard sciences to broaden his perspective on life. Being a premed was tough, and he worked hard. So hard, in fact, that he missed two Grateful Dead concerts and a campus appearance by Bruce Springsteen. But he liked being on the water and he joined the Duke sailing club and enjoyed a few special trips through the Bahamas. Ed graduated from college in 1978.
Duke Chapel (from KEnZPhotography)
He worked in a virology lab for six months and then taught white-water canoeing before going to medical school at the University of Maryland. The study of medicine was hard and, as a “mere mortal” he was tested, he reflected.

At the end of his "exciting, exhausting, and humbling" freshman year of basic science, he took a one-month rotation with a Dr. Greg Pinkerton in Eglon, West Virginia. This young idealistic doctor had only finished his internship, and yet he was the town physician. Ed had a formative experience;  Dr. Pinkerton was a good teacher and kind to all. “Hey! This might be something I could do,” he thought to himself, excitedly.

That was his first mentor, but the infectious disease specialist Dr. Frank Calia and rheumatologist Dr. Wolfe Blotzer “made us better than we believed ourselves to be. He helped us to develop confidence,” noted Dr. Rogers. His first encounter with Dr. Blotzer was at an hour-long clinical-correlation lecture where Wolfe lamented that the average student remembers only the first five minutes of a talk.

The evidence of that? Well, Ed said, with a laugh, that he recalled Dr. Blotzer’s introductory remarks, but that he had “no idea what he said after that.” An hour really is too long, and maybe the TED Talk rule of no more than 18 minutes makes sense. Attention wanders after even ten minutes.  (I can sense that you are beginning to lose focus already, your thoughts are probably headed somewhere else. Please pay attention. Try to stay in the present moment.)
J. Wolfe Blotzer, M.D.
But after a talk people do remember how they felt; the primitive emotional limbic system is slow to forget.

Anyway, Dr.Blotzer popped up again teaching him physical diagnosis during the second year. He demonstrated how to take a “patient-focused” history that “asked about the person” and “how the illness affected their life.” This mantra was repeated over and over; it eventually sunk in.

Through medical school, Ed didn’t especially take kindly to surgery or obstetrics, but he enjoyed everything else. He decided to go into the broad field of internal medicine. When the time came for residency Wolfe showed up again and advised Ed to take a look at the York Hospital program. He did that and was quite impressed by the strong medical staff; they liked him, and he “matched.” He came to York in 1983.

“Did you bring something different (than your peers) to the practice of medicine here?” I asked.

Pausing briefly, and thinking carefully, he said Yes. He felt that he brought himself. "I thought I was a good listener," he said, "and I felt strongly about the importance of self-care and lifestyle changes as being fundamental to one's health and well-being." And his desire to get to know his patients through ongoing relationships over time, to take the long and holistic view of good health, not simply illness, as was the focus in medical school.

After finishing his residency he did a fourth year as Chief Resident.  Dr. Rogers then joined the private practice with Drs. Fred Kephart and Steve Kreiger in 1987. He quickly saw that the medicine he was taught in school did not always address the patient’s real needs. 

Many (if not most) of the people a doctor sees have chronic conditions and vague symptoms that can’t be cured or alleviated by specific medicines or surgical techniques. Anxiety and fear about illness, and about life’s struggles, make things worse. It is said that a caring compassionate doctor can help alleviate suffering just by his or her presence. The placebo (“placebo” means “I will please”) response in the effective medical encounter is powerful and is accompanied by changes in brain chemistry and neural activity (as I am told by my husband).     

In his mid- to late-thirties Dr. Rogers tried mindfulness meditation to help him connect with the mysteries that still tugged at him. He took up a regular practice of this, and it helped. It then occurred to him that he could bring this gift of self-awareness to his patients as part of a holistic approach to health. This would also include informed self-care, balanced healthful nutrition, regular physical exercise (including yoga), other relaxation techniques, and restful sleep. But he did not know how to proceed.

He found a three-day workshop for the teaching of stress-reduction to cancer patients. Someone advised him to “check out Herbert Benson,”  the Harvard cardiologist who described “The Relaxation Response.” This idea was based on meditation traditions but stripped of their overtly spiritual or religious features. It was geared to help his heart patients cope with the stress that affected their cardiovascular system. The stress that delayed recovery from acute events and it often worsened the underlying disease.   
Dr. Jon Kabat-Zinn with Dr. Herbert Benson
Dr. Rogers took up the challenge. He did three intensive retreats with Dr. Benson’s group, and he was energized. He then was fortunate to meet Dr. Jon Kabat-Zinn, developer of Mindfulness-Based Stress Reduction (MBSR), and did two stimulating workshops with him. Good scientific research into the emotional and physical effects of meditating and yoga was just beginning to be available, making these “new age” or “alternative” practices slightly more acceptable to an ever wary medical establishment.

(Several decades ago “someone” handed me a book, The 28-Day Yoga Exercise Plan, to help me give up my seemingly-harmless “social” smoking. The slim woman in the stark black-and-white photos wore a pale leotard and matching tights; the now-ubiquitous patterned and colorful yoga pants had not been invented. I managed to do some of the positions and easily stopped smoking. Did the yoga itself help me stop, or did the giving of the book? Or were both needed?)
"I can't breathe, I can't breathe..."
The meditation and breathing techniques Dr. Rogers learned from the masters helped him cope with his own stress of raising two daughters (with his ever-supportive wife) and “working too many hours a day” in a busy primary care office. With this experience, he was ready to share his knowledge; he knew he had something. 

One day he cornered one of the York Hospital administrators, and, with his usual zerizut (see below), he said that running a stress reduction program and teaching meditation would be a great idea for the community. But York was not quite ready. 

Undeterred, Dr. Rogers said to himself that he and his patients were ready.

He started slowly with his office staff (practicing on them), and they mediated together during lunch break. (I hope no one was so relaxed that they fell sound asleep and couldn't get back to work.) He then cautiously offered simple guided meditation exercises to a few of his patients. After a while, he developed the confidence that he “could teach this.”

A year after his idea of an innovative program for stress reduction was nixed such things had caught on elsewhere, and the York Health System was more open to it and the broad field of complementary medicine including acupuncture, massage, yoga, tai chi, and nutrition. The mind-body interaction was integral to a holistic approach to well-being.

So, along with psychologist Jere (Kottkamp) Howell, Dr. Rogers started the program with eight-week stress reduction sessions modeled after Dr. Benson’s approach. His co-leader unexpectedly left the area the following year (2000) and he then ran the comprehensive Mind-Body Center himself (and worked full-time in his regular practice) until 2014. He was very happy to see the successes (and that mindfulness itself was rapidly becoming mainstream and part of our culture). 

He enjoyed the challenge of spreading the word and the practice of mindful attending to the present moment.

Over the years Ed kept up his personal practice of meditation and mindfulness. He learned to take a few deep breaths as a “sacred pause” and to feel his feet firmly planted on the floor before opening the exam room door to warmly greet the next patient. He learned to “focus” intently, to listen closely with compassion, and to give his patients “the time they need.” 

What are the effects of non-judgmental conscious awareness of the present moment?  The practice of mindfulness meditation, often focusing intently on the breath and letting intruding thoughts pass without judgment, can induce the so-called “relaxation response” described by Dr. Benson. This voluntary activity engages the parasympathetic limb of the autonomic nervous system, the system of “rest and digest.” Blood pressure, pulse, and muscle tension decrease, and markers of inflammation (like CRP and interleukin-6) diminish, as stress hormones of “fight or flight” (such as adrenaline and cortisol) fall. This sympathetic/parasympathetic balance is tipped and the effects are widespread. 


Functions of the autonomic nervous system
Brain structure is also affected. One study of new meditators showed that as little as an eight-week course in Kabat-Zinn’s MBSR resulted in increased gray matter in brain areas associated with learning, memory, and control of emotion including the hippocampus. There was a decrease in the density of neuronal gray matter in the amygdala, the key site of the fight or flight responses of fear and anxiety (Marchant, p. 170). 
Hotzel, BK Psych. Res. 2011; 191(1): 36-43
Dr. Rogers told me about studies on telomeres. (I had absolutely no idea what he was talking about but my husband helped, once again.) Telomeres are structures at the ends of strands of DNA, and the longer the telomere the longer the life of the cell it is in.  The enzyme telomerase slows the age-related shortening of the telomeres. Studies have shown that meditation may lead to increased telomerase activity, and may slow the aging process (Goleman and Davidson, p. 177).

Experienced meditators and veteran yoga practitioners likely have long-lasting changes in brain structure and connectivity, and there are new enduring "traits" not simply passing "states." There is much to learn about how mindfulness and other forms of meditation modify the brain and affect the autonomic nervous system (and the endocrine and immune systems), but there has been little doubt for thousands of years that what happens is beneficial. 

How the practice (and some type of meditation is seen in all religious traditions) affects the soul and informs ethical (social) behavior may be even more important, and a more profound mystery.     

Three months into “the very edge of retirement,” Dr. Rogers feels that “in the long run” he did what he “set out to do.” He rediscovered some wonderful ancient tools to help himself in his own spiritual journey and tools to help his patients cope with illnesses and suffering to bring about well-being. He doesn’t know what the future holds as he and his wife move to Vermont (one daughter is in Boston and the other lives in Upstate New York) but, as Ed says, “that’s exciting.”

There is a Vipassana, or Insight, Meditation Center a few minutes from where they are moving to, and Dr. Rogers plans to check it out.



Sitting quietly,
Doing nothing,
And the grass grows by itself

(Matsuo Basho 1644-1694)




Photo by S.C.


Readings:

1. Benson, Herbert, M.D. Beyond the Relaxation Response. New York: Berkley Books, 1984. (Still relevant.)

2. Golman, Daniel and Davidson, Richard J. Altered Traits: Science Reveals How Meditation Changes Your Mind, Brain, and Body.  New York: Avery, 2017. (The best review of the science.)

3. Hittelman, Richard. richard hittleman's Yoga 28-day exercise plan. New York: Workman Publishing Company, 1969. (For the pictures.)

4.  Marchant, Jo. Cure: A Journey into the Science of Mind Over Matter. New York: Broadway Books, 2017. (Highly recommended.)

A Definition:

Zerizut: A Hebrew word that is often translated as “zeal,” “alacrity” or “promptness.” Zerizut is the spark that catalyzes us to quickly and effectively do the things that need to be done. However, according to Alan Morinis, it may more accurately mean clear, deliberate, single-mindedness. This may be achieved, of course, through a meditative practice (see article).