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| Dr. McGuinness |
“Thanks for asking me,” he answered.
“Thanks for saying yes. This is not easy to do.”
“Which part? You or me?”
“Both,“ I say, as we laugh.
Dr. Tim McGuinness said that he has never been one to talk about himself--that is not his style. I told him that this has been my experience with almost all of the doctors interviewed for these stories. But once they begin talking, and I can keep myself from interrupting the flow, they can open up and go on for two hours.
So Tim asked where he should start, and I suggested with his family. And so he did.
Family and Before Medical School
His father, born in the Lehigh Valley of Eastern Pennsylvania, was a Border Patrol officer in Texas in the early 1950s. It was a very humanitarian service then. While there were some people that they had to apprehend and deport, they often took care of people “walking in the hinterlands of South Texas” that needed water, a meal, and medical care. Tim’s mother (also from the Lehigh Valley) was a nurse.
Because of his father’s job in immigration, Dr. McGuinniss and his younger brother had the opportunity to experience life in several quite different places. While he spent most of his childhood in Laredo, Texas, he also lived for a while at the Canadian border, and (as a high school sophomore and junior) in “idyllic” Hawaii (toward the end of the Vietnam War, during which refugees came through the islands ).
He finished high school in 1971 in Corpus Christie, Texas, sitting on the Gulf of Mexico, and went to Texas A&I University (now, since 1993, Texas A&M) in Kingsville, South Texas (where he was born). Tim said that he “always wanted to be a doctor” (reportedly since he was only three or four years old), but as he was a B student in college, and admission to medical school in the U.S. was very competitive, he decided to do a Master’s in microbiology (also at A&M).
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| College Hall at Texas A&M Kingsville (Credit: A&M) |
Medical School, Internship, and Public Health Service
He applied to medical school as a graduate student and was accepted to the Texas College of Osteopathic Medicine (TCOM) in Fort Worth. Tim attended by way of the generous Public Health Service program. This covered school tuition and fees, and provided a stipend for living in exchange for a promise to practice in an underserved area for as many years as the scholarship covered.
One day, as an eager second-year student learning about disease, he felt a lump in his neck and had someone look at it (more about this later).
After he finished medical school and took a rotating internship (doing surgery, internal medicine, ER, OB/GYN, etc.), Dr. McGuinness decided to fulfill his Health Service obligation as a solo practitioner in Del Rio, Texas, a medically underserved area sitting directly on the border. Why solo, and not in a clinic? He told me that he didn’t like the idea of “being told how to take care of patients by non-medical administrators.”
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| International Bridge spanning the Rio Grande and connecting Del Rio, Texas with Ciudad Acuna, Mexico (Credit: Ronald Castle) |
The experiences in this fragile community affected him deeply, and as he looked at the texts he collected in his bookshelf, he realized that he had developed an interest in Women’s Health, and especially in gynecologic cancer.
What to do next? As part of his four years of government obligation, Dr. McGuinness spent a month at an Indian Health Service clinic in Oklahoma. While there, he met a fellow physician who had trained at York Hospital. Tim was intrigued by his colleague’s glowing description of the place and the program, and he said to himself, ”That’s where I’ve got to go!"
Residency, Fellowship, and Initial Practice
And as Dr.McGuinness did his “great” OB/GYN residency at York Hospital, he couldn’t wait to get to work every day. What he had been previously told about the staff (including Drs. George Johnson, Hank Carter, Brad Myers, and Jay Jackson) was true. They were, he said, “superb teachers and surgical beasts.” He was also taught by experts who came up to York from Hopkins (including the renowned GYN cancer specialist Dr. Neil Rosenshein–"A prince of a man,” according to Tim). All in all, Tim had a wonderful time as a resident.
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| Dr. Mangan |
The next six years in Philly were quite active as local residents and women from the distant suburbs sought knowledgeable specialty care for gynecologic cancers. In fact, the program was busier than the same services at Penn, Temple, and Fox Chase.
But the big insurance companies (including US Healthcare) were in a race to be “the lowest paying people in town.” As the increasingly inadequate reimbursements could no longer cover the costs of the practice, the well-regarded group was pushed to near bankruptcy. Dr. McGuinness had two kids in high school, and he needed a secure way to provide for them.
Return to York
Dr. Nicolas Simon, hoping to recruit a fellowship-trained gyn-oncologist to York, called Dr. McGuinness to ask if he knew of anyone who might be interested. Tim’s response? “Yeah, you’re talking to him.”
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| Michelle |
His wife Janet (an OR nurse) planted the idea of having him start a fellowship program in York. He listened to her and, over time, he trained ten fellows (“good people”) who, in turn, helped lighten his day-to-day workload. In subsequent years, they were able to add attending staff from the graduates. Dr. McGuinness practiced the demanding art of gynecologic oncology in York for 16 years before retiring at age 62.
Advancements and Other Changes
He saw many improvements in his chosen field over the decades. Though he was initially trained as a “big hole” surgeon, he learned to do the tricky laparoscopic procedures, and he was happier when robot-assisted surgery made complex cases easier and much more precise.
He was also a witness to dramatic changes in the non-surgical aspects of caring for women with cancer. He was glad when Zofran, “a miracle drug,” virtually eliminated the “almost unconscionable” misery of intense chemotherapy-associated nausea (that sometimes started even before the chemo infusions, in a Pavlovian manner, he noted). Unlike older, much less effective, treatments for nausea, Zofran directly blocks the effects of the serotonin surge released by the gut at the brainstem chemoreceptor trigger zone and the vomiting center. It may also dampen general awareness of internal body signals. It made the dreaded chemo sessions tolerable.
When Dr. McGuinness was in Philadelphia, he had “the extreme displeasure” of watching three young girls die with cancer of the uterine cervix. He is glad that this might be a thing of the past. Virtually all cervical cancers are caused by persistent infection with one of the HPV viruses. Vaccination against HPV with Gardasil (approved in 2006) by age 11 or 12 (before sexual activity) may prevent up to 90% of invasive cervical cancers.Ovarian cancer that has spread beyond the ovary (the vast majority of cases, sadly) is “very difficult to eradicate,” said Dr. McGuinness. Localized tumors, those few that are curable, are usually picked up incidentally when looking for something else. But the most recent “biologic” and immune and targeted therapies for ovarian (or fallopian or primary peritoneal) cancer can sometimes result in a manageable “chronic disease” with long- term survival. The complex science behind these new (and emerging) therapies is truly remarkable.
Importantly, women with BRCA gene mutations are at extreme risk of developing ovarian cancer (maybe up to 60% with BRCA-1 defects, considerably less with BRCA-2), and may be candidates for prophylactic ovariectomy when they are beyond their childbearing years. Intensive screening to identify small tumors early on, when they can be fully removed, hasn't worked out yet.
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| Risk of breast and ovarian cancer and BRCA mutations (Credit: Myriad Genetics) |
He has seen, and is pleased, that there is now more attention to alleviating the heavy psychological aspects of receiving a diagnosis of cancer and living with it, including the ever-present fear of recurrence.
He Retires from Practice to Live Near the Beach
So, sixteen years after starting the division of gynecologic oncology in York, and at 62, Dr. McGuinness chose to leave practice behind. He and his wife, he said, wanted to “live near the beach.” (Wouldn’t most of us like a permanent beach vacation?) Well, as they looked around, they saw that there were no easily affordable sunny spots along the East Coast.
The Caribbean was an option, but was crossed out due to the risk of hurricanes. So they turned further south. Tim speaks passable Spanish, and they considered Mexico, but thought it was too dangerous. After months of online study about where to settle as expats, they decided to try Ecuador.
They visited and stayed with an American couple. They (meaning his wife) had been looking at a place in Manglaralto, a quiet, tranquil village three hours by car from Guayaquil, the cultural and financial center of Ecuador. They were not sure where it sat, but the two-story wooden house that Janet found online turned out to be a baseball's throw from the beach. It was perfect. And they fell in love with it. So they did what you were not supposed to do in these situations–they immediately bought it (for cash, the only option).
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| Beach at Manglaralto (Credit: Expedia) |
The Pandemic and an Unexpected Tragedy
They were friendly with the locals, as well as with expats from Romania and Venezuela (and less so with displaced Americans). But things began to change when the pandemic hit. There was great fear of contagion, serious illness, and death.
To limit the spread of the virus, you could not leave your house after five in the evening, and you could only drive every other day. For nearly two years, they left home to shop or to go to the pharmacy. When vaccines became available, the only one used in Ecuador was the inactivated virus from China. It was not nearly as effective as the novel Pfizer and Moderna mRNA vaccines. Dr. McGuinness admitted that healthcare in Ecuador wasn’t “all that great.” So as soon as he and his wife were permitted to travel, they came back home to be immunized.
But their six-year stay by the Pacific Ocean was “tainted” further by a family tragedy when Tim’s brother-in-law and sister-in-law were staying with them. His sister-in-law was tired, went to the bathroom, fell off the commode, bumped her head, and began acting “kind of weird.” She was reluctant to get things checked out, but she finally agreed to go to the small local hospital.
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| The 2-story Dr. Liborio Panchana Sotomayor hospital (a typical rudimentary healthcare facility not too far from Manglaralto) |
That sad experience, the stifling pandemic restrictions, and the awareness that healthcare in Ecuador was somewhat lacking and that they were three hours from the nearest major hospital led to the decision to return home.
Return to York, and We Share Stories
He and Janet came back to York four years ago. He planned to pass time by reading (he especially enjoys David Baldacci novels), playing (very basic) blues guitar, or traveling (their dogs currently hold them back). But he was coaxed into seeing patients in the office again to help out Dr. Eav Lim until they are able to recruit a second full-time gynecologic oncologist. But he doesn’t do surgery anymore.
Deep into the interview, after hearing Dr. McGuinness talk about his extensive career taking care of women with gynecologic cancers, I quietly told him that I was an ovarian cancer survivor. I told him that I was 27 in 1981 and living in Syracuse when the stage IV disease was found. I took Alkeran tablets daily; they made me sick.
After we moved to Baltimore and had the “second-look” surgery a year after diagnosis, there was residual tumor, and I was flatly told that “there are things we can do.” Shaken, I sought a second opinion. I saw Dr. Rosenshein. He phoned me early one morning after the visit (I was still in bed). He had just come back from a conference and had cutting-edge information. Stay with what you are doing, no more chemotherapy, he said. I was overjoyed. As he predicted, my unusual cancer disappeared. I was lucky. But the damage to my psyche through the ordeal was real and long-lasting. And I felt alone. Having never met a woman who survived ovarian cancer, even 40 years later, has added to this heavy emotional isolation.
As I spoke, Dr. McGuinness looked at me and listened intently, and with obvious compassion. After a brief pause, he gently told me that he was a survivor too. You see, the lump that had popped up high on his neck when he was a second-year medical student in Texas was a Hodgkin’s lymphoma. When the surgeon who operated on him relayed the diagnosis, he was painfully blunt: “You’ve got it, chief.”
The young, optimistic medical student instantly imagined the worst–the only person he had met with Hodgkin’s, a colleague in graduate school whom he had known only briefly, had died within two months of diagnosis. What was Tim to think? Would he live to see another spring, his favorite season? But the stage IA presentation of Hodgkin’s was often curable even then, and the lymphoma shriveled away with radiation therapy.
We are both survivors, yes, but the emotional impact, the shock, of facing our mortality at such a young age can last forever. And it molds who we are, and how we respond to the world. Among other things (and Dr. McGuinness quickly agreed), it fosters a positive sense of gratitude for being alive. Each new day is a gift.
And, by the way, as my husband often reminds me, “everything is practice for later.”
Suggested Readings:
1. Anonymous. Cervical Cancer Causes, Risk Factors, and Prevention. National Cancer Institute at The National Institutes of Health. Accessed at https://www.concer.gov/types/cervical/causes-risk-prevention. Updated 8/2/2024. ("Nearly all cervical cancers could be prevented y HPV vaccination, routine cervical cancer screening, and appropriate follow-up treatment when needed.")
2. Hillmann, J., Maass, N., Bauerschlag, D.O. et al. Promising new drugs and therapeutic approaches for treatment of ovarian cancer-- targeting the hallmarks of cancer. BMC Med 23, 10 (2025). (They conclude: Ovarian cancer "remains the most lethal gynecologic cancer...but many new strategies to improve [a] patient's outcome appear upon the horizon..[including] targeted therapy, immunotherapy, gene therapy, and drug-conjugates.")
2. Hodgkinson, Katherine, Butow, Phyllis, et al. Long-term survival from gynecologic cancer: Psychosocial outcomes, supportive care needs and positive outcomes. Gynecologic Oncology, 104 (2), 381-389, 2007. (An Australian single-institution self-report study of disease-free women up to 8 years following successful treatment revealed that while 68% had positive outcomes emotionally, 19% had post-traumatic stress disorder and 29% had clinical anxiety, often regarding fear of recurrence. Many women reported unmet existential needs.)
By Anita Cherry, 6/17/26
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| Anita Cherry, Self-portrait, 1981, Watercolor on paper, 10 x 12 inches |
































